Studied at the University of Zurich, then took the exams in Lausanne where, after failing the first time, he passed, but was refused the post of psychiatrist at Cery. He then went to Munich and became a privatdocent in 1877. In 1878 he undertook an expedition to Colombia, but gave up when his companion died. In 1879, he became professor of psychiatry at the University of Zurich. In 1889, he took up the fight against alcoholism. He was undoubtedly one of our country's greatest psychiatrists.Autograph letter signed Yvorne, 01.09.1908 to a friend "... et moi qui déteste les hommages personnels; je voudrais rentrer sous terre ...".; fragment with autograph lines and signature; autograph lines signed dated 13.03.00; commemorative stamp.